about
The Blue Brain Open Platform is a groundbreaking open-source simulation neuroscience platform developed by the Blue Brain Project.
Our mission is to advance the understanding of the brain by providing access to state-of-the-art data exploration, modeling, and simulation techniques.
By integrating a wide range of open-source tools and models, especially those created by Blue Brain, we offer an invaluable resource for the neuroscience community to leverage simulation neuroscience.
Features
of the blue brain open platform
The Blue Brain Open Platform enables atlas-driven exploration of brain data, from molecular models of metabolic systems to single-cell morphologies and complex brain region simulations.
Users can customize their models, run personalized simulations, and leverage machine learning for comparative data analyses. This flexibility accelerates and enhances neuroscience research.
Origin
of the blue brain open platform
Since its inception in 2005, the Blue Brain Project has been a leader in establishing simulation neuroscience as a complement to experimental and theoretical neuroscience. It has achieved this primarily by creating biologically detailed digital reconstructions and simulations of the mouse brain.
All the tools and models created and used by Blue Brain are brought together in one platform to be shared with the neuroscience community. This is the result of significant investment and collaborations with more than 30 institutes worldwide, underscoring the importance of international cooperation and open science.
Open Platform Brochure
The Blue Brain Open Platform offers the capability of exploring, building and simulating brain models. Discover a brief overview in this introduction to the platform.
Introduction to Digital Brain Models
The Blue Brain Open Platform uses digital brain models developed by the Blue Brain Project. Learn about the different models in this brief overview.
Biological Fidelity
The Blue Brain Open Platform is a fully integrated tool for simulation neuroscience using a series of algorithms and models. In this overview, the structural and functional validations of the models are described.
microcircuits
A cortical microcircuit model comprises all six cortical layers with a horizontal extent that captures the entire dendritic tree of the most central neurons. Neurons within have the same anatomical and physiological level of detail as single neuron models. All synapses between the contained neurons are included, plus more abstract models of thalamo-cortical axons that serve as user-controlled inputs. This setup can be used to study the local processing of thalamic inputs, and the roles of individual subpopulations during that process.
The Blue Brain Project
In Short
Swiss-based initiative
Hosted at the Ecole Polytechnique Fédérale de Lausanne (EPFL)
19+ years pioneering simulation neuroscience
Around 40 international projects
In collaboration with 35+ institutes
270+ peer-reviewed publications
1,000+ contributing authors
20k+ citations garnered
Open Science: 260+ public repositories released
Simulation neuroscience
Discover the benefits
Complementing
theory and experiments
While simulation neuroscience is a powerful tool, it complements rather than replaces experimental and theoretical approaches.
Virtual experiments allow users to prototype experiments, test hypotheses and explore a wide range of applications that are difficult to do in experiments directly.
